This course is designed to introduce 400 level students of Biochemistry & Nutrition programme to operation of latest biochemical equipment. They will be taught the various methods of research, assimilation and dissemination of information. Effective use of library, preparation of dissertations or theses, as well as how to write papers for journal publications and conferences will be explained to the students extensively. Experimental design as well as analysis and interpretation of experimental data will be explained.

There is the need to learn and teach the students how to operate various new biochemical equipment, as a result of new advancements in science and technology. Methods of research and experimental design are vital to the development of new drugs and new scientific findings. Analysis and interpretation of such data will lead to generation of information. Assimilation and dissemination of information with effective use of the library is essential towards successful preparation of dissertations and papers for journal publications as well as conference.

The course is designed to introduce 400 level students of Biochemistry & Nutrition to nutrient availability of foods and the health issues associated with exogenous materials that come in contact with foods. The biochemical implications of such natural and synthetic chemicals are the focus of this course.

The exposure of man to exogenous substances in foods and their metabolic profiles are very important to food and nutritional scientists so that relatively safe alternatives can be employed during cultivation, harvesting, storing, processing and handling of foods.

At the end of the course, the students should be able to

-describe food constituents and their sources

-describe the structures and functions of nutrients

-explain the adverse effects of food additives, pesticides, drugs, nutrient supplements, carcinogens, contaminants, etc

-discuss the metabolic profiles of some of these chemicals

-explain the legal issues involved in their use

The course is designed to introduce 300 level students of Biochemistry and Nutrition to the nature, properties and catalytic role performed by enzymes so that they can understand the mechanism by which enzymes regulate biological processes. General properties of enzymes, classification and nomenclature of enzymes, and active site features of enzymes will be described. The mechanism and kinetics of enzyme catalysed reaction for single substrate and bisubstrate reactions will be described to gain insight into the reaction mechanism of enzymes.

The effects of certain factors like temperature, pH, ions and inhibitors will be described to see how they affect the rate of enzyme catalysed reactions. The course will also introduce the students to methods of isolation, purification and characterization of enzymes. The students will be able to apply these methods to obtain purified enzyme which they can use for kinetic experiments. The role of vitamins and coenzymes in biochemical processes especially as enzyme cofactors will also be described.

Enzymes are biological catalysts that mediate nearly all biochemical processes that comprise life. Since without enzymes metabolic processes cannot take place, it is therefore imperative for students of biochemistry to understand the following:

(i) Certain properties possessed by enzymes that facilitate their catalytic actions;

(ii) Mechanism of enzyme- catalysed reaction and factors affecting the rate of enzymatic reaction; (iii) Methods of generating and analysing kinetic data;

(iv) Method of obtaining purified enzyme for experimental purposes. All these will give the students insight into how enzymes regulate metabolic processes and enable them to generate, analyse and interprete kinetic data.

This course introduces students in the chemical, biological, and basic medical and health sciences to the study of biomolecules as the carbon-containing compounds that make up the various parts of the living cell and carry out chemical reactions that enable it to grow, maintain and reproduce itself, and also to use and store energy. Hence the structure of such biomolecules determines in what chemical reactions it is able to participate, and hence what role it plays in the cell’s life processes. Examples of biomolecules include nucleic acids, proteins, carbohydrates and lipids.